{
   "$schema": "https://json-schema.org/draft/2020-12/schema",
   "title": "MyOme Family Variant Testing Report",
   "description": "MyOme Family Variant Testing report object",
   "type": "object",
   "allOf": [
      {
         "$ref": "base.json"
      },
      {
         "properties": {
            "report_type": {
               "const": "FAMILY_VARIANT_TESTING",
               "type": "string"
            },
            "results": {
               "$ref": "#/definitions/FVTReportResults"
            }
         }
      }
   ],
   "definitions": {
      "FamilyVariantClassification": {
         "type": "object",
         "additionalProperties": false,
         "required": [
            "classification",
            "location",
            "variation",
            "variant_evidence",
            "interpretation_description",
            "familial_variant_detected",
            "zygosity"
         ],
         "properties": {
            "classification": {
               "title": "ACMG Classification",
               "$ref": "../../core.json#/definitions/ACMGPlusNegativeClassification"
            },
            "variantfinding_id": {
               "$ref": "../../ids.json#/definitions/VariantFindingId"
            },
            "finding_type": {
               "$ref": "../../core.json#/definitions/FindingType"
            },
            "location": {
               "type": "string"
            },
            "variation": {
               "type": "object",
               "$ref": "../../structs.json#/definitions/FamilyVariantVariation"
            },
            "variant_evidence": {
               "title": "Per Variant Evidence",
               "type": "string"
            },
            "zygosity": {
               "title": "Zygosity",
               "$ref": "../../core.json#/definitions/Zygosity"
            },
            "interpretation_description": {
               "title": "Interpretation Description",
               "type": "string"
            },
            "gene_info": {
               "title": "Gene Information",
               "type": [
                  "string",
                  "null"
               ]
            },
            "familial_variant_detected": {
               "title": "Result",
               "$ref": "../../core.json#/definitions/FamilialVariantResult"
            }
         }
      },
      "FamilyVariantTopline": {
         "description": "The report's main conclusion for Family Variant Testing",
         "title": "Topline Finding(s)",
         "type": "array",
         "minItems": 1,
         "items": {
            "allOf": [
               {
                  "$ref": "../../structs.json#/definitions/ToplineFinding"
               },
               {
                  "properties": {
                     "finding": {
                        "$ref": "../../core.json#/definitions/RareDiseaseToplineFinding"
                     }
                  }
               }
            ]
         }
      },
      "FVTReportResults": {
         "description": "Family Variant Testing ReportResults - simplified structure for targeted family variant analysis",
         "type": "object",
         "additionalProperties": false,
         "required": [
            "toplines",
            "next_steps",
            "classifications",
            "disclaimers"
         ],
         "properties": {
            "classifications": {
               "type": "array",
               "items": {
                  "$ref": "#/definitions/FamilyVariantClassification"
               }
            },
            "disclaimers": {
               "title": "Disclaimers",
               "type": "array",
               "items": {
                  "type": "string"
               },
               "example": [
                  "This test was developed, and its performance characteristics were determined, by MyOme, Inc., a clinical laboratory certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and College of American Pathologist (CAP) accredited to perform high complexity clinical laboratory testing. This test has not been cleared or approved by the U.S. Food and Drug Administration (FDA).",
                  "Like most tests, this test carries a risk of false negative or false positive results. Testing is unavailable for samples damaged by human error, lost/destroyed due to weather, transit issues or other problems beyond the control of MyOme. Test results should always be interpreted by a clinician in the context of clinical and familial data with the availability of genetic counseling when appropriate."
               ]
            },
            "next_steps": {
               "title": "Next Steps",
               "type": "array",
               "items": {
                  "type": "string"
               },
               "example": [
                  "These results should be interpreted in the context of this individual's clinical findings, family history, and other laboratory data.",
                  "Genetic counseling is recommended to discuss what these results mean for you and your family."
               ]
            },
            "toplines": {
               "$ref": "#/definitions/FamilyVariantTopline"
            },
            "methods": {
               "title": "Testing Methods",
               "type": "array",
               "items": {
                  "type": "string"
               },
               "description": "Methods used for family variant testing (e.g., Sanger sequencing, aCGH, etc.)"
            },
            "sample_limitations": {
               "title": "Sample Limitations",
               "type": "array",
               "items": {
                  "type": "string"
               },
               "description": "Sample specific limitations related to this report"
            },
            "limitations": {
               "title": "Test Limitations",
               "type": "array",
               "items": {
                  "type": "string"
               },
               "description": "Technical limitations specific to the testing methods used"
            },
            "family_context": {
               "title": "Family Testing Context",
               "type": [
                  "string",
                  "null"
               ],
               "description": "Context about the family variant being tested"
            }
         }
      }
   }
}