{
   "$schema": "https://json-schema.org/draft/2020-12/schema",
   "title": "Common Tyrer-Cuzick Types",
   "type": "object",
   "definitions": {
      "age_at_menarche": {
         "title": "Age At Menarche",
         "description": "Age at first menstrual period. Leave blank if unknown.",
         "type": "integer",
         "minimum": 0,
         "maximum": 99
      },
      "number_of_live_births": {
         "title": "Number Of Live Births",
         "description": "Leave blank if unknown.",
         "type": "integer",
         "minimum": 0,
         "maximum": 50
      },
      "age_at_first_birth": {
         "title": "Age At First Birth",
         "description": "Leave blank if unknown.",
         "type": "integer",
         "minimum": 0,
         "maximum": 99
      },
      "menopausal_status": {
         "$ref": "../core.json#/definitions/MenopausalStatus"
      },
      "age_at_menopause": {
         "title": "Age At Menopause",
         "description": "Leave blank if unknown.",
         "type": "integer",
         "minimum": 0,
         "maximum": 99
      },
      "history_of_hyperplasia": {
         "title": "History Of Hyperplasia",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "history_of_atypical_hyperplasia": {
         "title": "History Of Atypical Hyperplasia",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "history_of_lcis": {
         "title": "History Of LCIS",
         "description": "Lobular carcinoma in situ (LCIS)",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "history_of_ovarian_cancer": {
         "title": "History Of Ovarian Cancer",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "age_at_diagnosis_of_ovarian_cancer": {
         "title": "Age At Diagnosis Of Ovarian Cancer",
         "type": "integer",
         "minimum": 0,
         "maximum": 99
      },
      "hormone_replacement_therapy_use": {
         "title": "Hormone Replacement Therapy (HRT) Use",
         "type": "string",
         "anyOf": [
            {
               "title": "Never",
               "type": "string",
               "enum": [
                  "NEVER"
               ]
            },
            {
               "title": "Previous user (more than 5 years ago)",
               "type": "string",
               "enum": [
                  "GT_5_YEARS_AGO"
               ]
            },
            {
               "title": "Previous user (less than 5 years ago)",
               "type": "string",
               "enum": [
                  "LT_5_YEARS_AGO"
               ]
            },
            {
               "title": "Current user (or stopped using less than 12 months ago)",
               "type": "string",
               "enum": [
                  "CURRENT"
               ]
            }
         ]
      },
      "type_of_hormone_replacement_therapy_taken": {
         "title": "Type Of Hormone Replacement Therapy (HRT) Taken",
         "type": "string",
         "enum": [
            "OESTROGEN",
            "COMBINED",
            "UNKNOWN"
         ]
      },
      "length_of_time_taking_hormone_replacement_therapy": {
         "title": "Length Of Time Taking Hormone Replacement Therapy (HRT)",
         "description": "Round to the nearest decimal point (e.g. 4.5 years)",
         "type": "number",
         "minimum": 0
      },
      "length_of_future_time_intended_to_take_hormone_replacement_therapy": {
         "title": "Length Of Future Time Intended To Continue Taking Hormone Replacement Therapy (HRT)",
         "description": "Round to the nearest decimal point (e.g. 4.5 years)",
         "type": "number",
         "minimum": 0
      },
      "length_of_time_since_last_taking_hormone_replacement_therapy": {
         "title": "Length Of Time Since Last Taking Hormone Replacement Therapy (HRT)",
         "description": "Round to the nearest decimal point (e.g. 4.5 years)",
         "type": "number",
         "minimum": 0
      },
      "genetic_testing": {
         "$ref": "../core.json#/definitions/BreastCancerGeneticTesting",
         "title": "Genetic Testing Of The Woman"
      },
      "genetic_testing_of_father": {
         "$ref": "../core.json#/definitions/BreastCancerGeneticTesting",
         "title": "Genetic Testing Of The Woman's Father"
      },
      "mother": {
         "$ref": "#/definitions/TyrerCuzickFamilyHistory",
         "title": "Mother"
      },
      "paternal_grandmother": {
         "$ref": "#/definitions/TyrerCuzickFamilyHistory",
         "title": "Paternal Grandmother"
      },
      "maternal_grandmother": {
         "$ref": "#/definitions/TyrerCuzickFamilyHistory",
         "title": "Maternal Grandmother"
      },
      "sisters": {
         "title": "Sisters",
         "type": "array",
         "items": {
            "type": "object",
            "properties": {
               "personal_history": {
                  "title": "Personal History",
                  "$ref": "#/definitions/TyrerCuzickFamilyHistory"
               },
               "daughters": {
                  "title": "Daughters (Nieces)",
                  "type": "array",
                  "items": {
                     "$ref": "#/definitions/TyrerCuzickFamilyHistory"
                  }
               }
            }
         }
      },
      "paternal_aunts": {
         "title": "Paternal Aunts",
         "type": "array",
         "items": {
            "type": "object",
            "properties": {
               "personal_history": {
                  "title": "Personal History",
                  "$ref": "#/definitions/TyrerCuzickFamilyHistory"
               },
               "daughters": {
                  "title": "Daughters (Cousins)",
                  "type": "array",
                  "items": {
                     "$ref": "#/definitions/TyrerCuzickFamilyHistory"
                  }
               }
            }
         }
      },
      "maternal_aunts": {
         "title": "Maternal Aunts",
         "type": "array",
         "items": {
            "type": "object",
            "properties": {
               "personal_history": {
                  "title": "Personal History",
                  "$ref": "#/definitions/TyrerCuzickFamilyHistory"
               },
               "daughters": {
                  "title": "Daughters (Cousins)",
                  "type": "array",
                  "items": {
                     "$ref": "#/definitions/TyrerCuzickFamilyHistory"
                  }
               }
            }
         }
      },
      "daughters": {
         "title": "Daughters",
         "type": "array",
         "items": {
            "$ref": "#/definitions/TyrerCuzickFamilyHistory"
         }
      },
      "brothers_daughters": {
         "title": "Brothers' Daughters With Breast Cancer",
         "type": "array",
         "items": {
            "$ref": "#/definitions/TyrerCuzickFamilyHistory"
         }
      },
      "paternal_half_sisters": {
         "title": "Paternal Half Sisters",
         "type": "array",
         "items": {
            "$ref": "#/definitions/TyrerCuzickFamilyHistory"
         }
      },
      "maternal_half_sisters": {
         "title": "Maternal Half Sisters",
         "type": "array",
         "items": {
            "$ref": "#/definitions/TyrerCuzickFamilyHistory"
         }
      },
      "paternal_uncles_daughters": {
         "title": "Paternal Uncles' Daughters (Cousins)",
         "type": "array",
         "items": {
            "$ref": "#/definitions/TyrerCuzickFamilyHistory"
         }
      },
      "maternal_uncles_daughters": {
         "title": "Maternal Uncles' Daughters (Cousins)",
         "type": "array",
         "items": {
            "$ref": "#/definitions/TyrerCuzickFamilyHistory"
         }
      },
      "father_had_breast_cancer": {
         "title": "Has The Father Had Breast Cancer?",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "brother_had_breast_cancer": {
         "title": "Has A Brother Had Breast Cancer?",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "breast_density_measure": {
         "title": "Breast Density Measure",
         "type": "string",
         "anyOf": [
            {
               "title": "Volpara\u00ae Volumetric Density (%)",
               "type": "string",
               "enum": [
                  "VOLPARA"
               ]
            },
            {
               "title": "VAS Percentage Density",
               "type": "string",
               "enum": [
                  "VAS"
               ]
            },
            {
               "title": "BI-RADS\u00ae ATLAS Density",
               "type": "string",
               "enum": [
                  "BIRADS"
               ]
            },
            {
               "title": "Not Available",
               "type": "string",
               "enum": [
                  "NOT_AVAILABLE"
               ]
            }
         ]
      },
      "breast_density_value_decimal": {
         "title": "Breast Density Value (0.00 to 100.00)",
         "description": "Value for Volpara\u00ae and VAS",
         "type": "number",
         "minimum": 0.0,
         "maximum": 100.0
      },
      "breast_density_value_birads": {
         "title": "Breast Density Value",
         "description": "Value for BI-RADS",
         "type": "string",
         "enum": [
            "ALMOST_ENTIRELY_FATTY",
            "SCATTERED_FIBROGLANDULAR DENSITY",
            "HETEROGENEOUSLY_DENSE",
            "EXTREMELY_DENSE"
         ]
      },
      "polygenic_snp_score": {
         "title": "Polygenic SNP Score",
         "description": "Log relative risk, decimal",
         "type": "number"
      },
      "name": {
         "title": "Name",
         "type": "string"
      },
      "had_breast_cancer": {
         "title": "Did They Have Breast Cancer?",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "breast_cancer_bilateral": {
         "title": "Was Breast Cancer Bilateral?",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "age_at_breast_cancer": {
         "title": "Age At Which They Developed Breast Cancer?",
         "description": "If unknown, then their current age or the age at which they died.",
         "type": "integer",
         "minimum": 0
      },
      "age_at_breast_cancer_bilateral": {
         "title": "Age At Which They Developed Bilateral Breast Cancer?",
         "description": "If unknown, then their current age or the age at which they died.",
         "type": "integer",
         "minimum": 0
      },
      "had_ovarian_cancer": {
         "title": "Did They Have Ovarian Cancer?",
         "$ref": "../core.json#/definitions/YesNoUnknown"
      },
      "age_at_ovarian_cancer": {
         "title": "Age At Which They Developed Ovarian Cancer?",
         "description": "If unknown, then their current age or the age at which they died.",
         "type": "integer",
         "minimum": 0
      },
      "TyrerCuzickFamilyHistory": {
         "type": "object",
         "properties": {
            "name": {
               "$ref": "#/definitions/name"
            },
            "had_breast_cancer": {
               "$ref": "#/definitions/had_breast_cancer"
            },
            "breast_cancer_bilateral": {
               "$ref": "#/definitions/breast_cancer_bilateral"
            },
            "age_at_breast_cancer": {
               "$ref": "#/definitions/age_at_breast_cancer"
            },
            "age_at_breast_cancer_bilateral": {
               "$ref": "#/definitions/age_at_breast_cancer_bilateral"
            },
            "had_ovarian_cancer": {
               "$ref": "#/definitions/had_ovarian_cancer"
            },
            "age_at_ovarian_cancer": {
               "$ref": "#/definitions/age_at_ovarian_cancer"
            },
            "genetic_testing": {
               "$ref": "../core.json#/definitions/BreastCancerGeneticTesting"
            }
         }
      },
      "TyrerCuzickFamilyHistoryWithDependencies": {
         "type": "object",
         "properties": {
            "name": {
               "$ref": "#/definitions/name"
            },
            "had_breast_cancer": {
               "$ref": "#/definitions/had_breast_cancer"
            },
            "had_ovarian_cancer": {
               "$ref": "#/definitions/had_ovarian_cancer"
            },
            "genetic_testing": {
               "$ref": "../core.json#/definitions/BreastCancerGeneticTesting"
            }
         },
         "dependencies": {
            "had_breast_cancer": {
               "oneOf": [
                  {
                     "properties": {
                        "had_breast_cancer": {
                           "enum": [
                              "NO",
                              "UNKNOWN"
                           ]
                        }
                     }
                  },
                  {
                     "properties": {
                        "had_breast_cancer": {
                           "enum": [
                              "YES"
                           ]
                        },
                        "breast_cancer_bilateral": {
                           "$ref": "#/definitions/breast_cancer_bilateral"
                        },
                        "age_at_breast_cancer": {
                           "$ref": "#/definitions/age_at_breast_cancer"
                        }
                     },
                     "dependencies": {
                        "breast_cancer_bilateral": {
                           "oneOf": [
                              {
                                 "properties": {
                                    "breast_cancer_bilateral": {
                                       "enum": [
                                          "NO",
                                          "UNKNOWN"
                                       ]
                                    }
                                 }
                              },
                              {
                                 "properties": {
                                    "breast_cancer_bilateral": {
                                       "enum": [
                                          "YES"
                                       ]
                                    },
                                    "age_at_breast_cancer_bilateral": {
                                       "$ref": "#/definitions/age_at_breast_cancer_bilateral"
                                    }
                                 }
                              }
                           ]
                        }
                     }
                  }
               ]
            },
            "had_ovarian_cancer": {
               "oneOf": [
                  {
                     "properties": {
                        "had_ovarian_cancer": {
                           "enum": [
                              "NO",
                              "UNKNOWN"
                           ]
                        }
                     }
                  },
                  {
                     "properties": {
                        "had_ovarian_cancer": {
                           "enum": [
                              "YES"
                           ]
                        },
                        "age_at_ovarian_cancer": {
                           "$ref": "#/definitions/age_at_ovarian_cancer"
                        }
                     }
                  }
               ]
            }
         }
      }
   }
}